Demis Hassabis project - long list

I'll search for DeepMind projects led by Demis Hassabis.Now I have enough information to compile a comprehensive list.

DeepMind Projects (Led by Demis Hassabis)

Games & Reinforcement Learning

Project Year Description
DQN (Deep Q-Network) 2013-2015 First deep RL agent to play 49 Atari games at superhuman level
AlphaGo 2016 First AI to beat world champion (Lee Sedol) at Go
AlphaGo Zero 2017 Self-taught Go AI, beat AlphaGo 100-0
AlphaZero 2017 Mastered Go, chess, and shogi from scratch
AlphaStar 2019 Grandmaster-level StarCraft II player
MuZero 2019-2020 Mastered games without knowing rules
Agent57 2020 First agent to outperform humans on all 57 Atari games
SIMA 2024 Generalist agent for 3D video games
SIMA 2 2025 Gemini-powered agent with self-improvement
Genie 1/2/3 2024-2025 World models generating interactive 3D environments

Science & Biology

Project Year Description
AlphaFold 2018 Protein structure prediction (CASP13 winner)
AlphaFold 2 2020 Solved protein folding problem (~90% accuracy)
AlphaFold 3 2024 Predicts all biomolecular interactions (proteins, DNA, RNA, ligands)
AlphaProteo 2024 Designs novel protein binders
AlphaMissense 2023 Predicts pathogenic genetic mutations
AlphaGenome 2024 Assesses genetic mutations underlying disease
Isomorphic Labs 2021 Drug discovery spinoff (heading to human trials 2025)

Mathematics & Algorithms

Project Year Description
AlphaTensor 2022 Discovered faster matrix multiplication algorithms
AlphaDev 2023 Found 70% faster sorting algorithms
AlphaGeometry 2024 IMO geometry problem solver (53% → 83% of problems)
AlphaGeometry 2 2024 Improved version solving harder problems
AlphaProof 2024 Formal mathematical reasoning (IMO silver medal level)
AlphaEvolve 2025 Evolutionary coding agent for algorithm discovery

Materials & Weather

Project Year Description
GNoME 2023 Discovered 2.2M new crystal structures, 380K stable materials
GraphCast 2023 10-day weather forecasts faster/better than traditional models
GenCast 2024 Probabilistic weather forecasting
WeatherNext 2 2025 Powers Google Search/Maps weather features

Healthcare

Project Year Description
Retinal Disease AI 2018 94% accuracy on 50+ eye diseases (with Moorfields)
AMD Prediction 2020+ Predicts macular degeneration progression
Streams 2016-2018 Acute kidney injury detection app (NHS)

Generative AI (post-Google Brain merger)

Project Year Description
Gemini 2023+ Multimodal LLM family (Nano/Pro/Ultra/2.0/2.5/3)
Gemma 2024 Open-weight LLMs
WaveNet 2016 Text-to-speech (powers Google Assistant)
Imagen 2022+ Text-to-image generation
Veo / Veo 2 / Veo 3 2024-2025 Text-to-video (up to 4K, synchronized audio)
Lyria 2024 Text-to-music generation
Gato 2022 Polyvalent multimodal model (604 tasks)

Other Notable Work

  • Neural Turing Machines (2014) – Neural networks with external memory
  • Differentiable Neural Computers (2016)
  • Dopamine reward prediction research (neuroscience contributions)
  • Data center cooling optimization (40% energy reduction for Google)